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Continuing education module from rxBriefcase. Discuss the etiology, pathophysiology, and communicability of oral herpes simplex viral (HSV) infection, including primary infection, latency, and recurrence of the virus; cold sores and identify their cause; Characterize patient presentation of oral recurrent herpes labialis (RHL), including the stages of a recurrent episode; methods for diagnosing oral RHL, canker sores, and other orofacial afflictions; non-prescription and prescription therapies for treating oral RHL including their classification, mechanism of action, adverse effects, and place in therapy; counsel patients with oral RHL about current therapies with an emphasis on non-prescription treatment, and techniques designed to avoid recurrence, relieve symptoms, and prevent the spread of infection.